Single cell multiomics identifies cells and genetic networks underlying alveolar capillary dysplasia
Minzhe Guo1, Yan Xu1, Kathryn A. Wikenheiser-Brokamp1, Joseph A. Kitzmiller1, Xin Sun2, Allen Wang2, Sebastian Preissl2, Jeffrey A. Whitsett1*
1Cincinnati Children's Hospital Medical Center, 2University of California, San Diego, *Corresponding author
Description
Single nucleus RNA-seq and ATAC-seq were performed on five human lungs with ACDMPV to identify cell types, gene expression patterns, regulatory networks, and cell-cell interactions underlying the pathogenesis of ACDMPV.