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Organoids Model Transcriptional Hallmarks of Oncogenic KRAS Activation in Lung Epithelial Progenitor Cells.
Dost AFM, Moye AL, Vedaie M, Tran LM, Fung E, Heinze D, Villacorta-Martin C, Huang J, Hekman R, Kwan JH, Blum BC, Louie SM, Rowbotham SP, Sainz de Aja J, Piper ME, Bhetariya PJ, Bronson RT, Emili A, Mostoslavsky G, Fishbein GA, Wallace WD, Krysan K, Dubinett SM, Yanagawa J, Kotton DN, Kim CF
Cell stem cell, 10 2020
Elevated FiO increases SARS-CoV-2 co-receptor expression in respiratory tract epithelium.
Myti D, Gunjak M, Casado F, Khaghani Raziabad S, Nardiello C, Vadász I, Herold S, Pryhuber G, Seeger W, Morty RE
American journal of physiology. Lung cellular and molecular physiology, 10 2020
A lung tropic AAV vector improves survival in a mouse model of surfactant B deficiency.
Kang MH, van Lieshout LP, Xu L, Domm JM, Vadivel A, Renesme L, Mühlfeld C, Hurskainen M, Mižíková I, Pei Y, van Vloten JP, Thomas SP, Milazzo C, Cyr-Depauw C, Whitsett JA, Nogee LM, Wootton SK, Thébaud B
Nature communications, 08 2020
A mechanistic model and therapeutic interventions for COVID-19 involving a RAS-mediated bradykinin storm.
Garvin MR, Alvarez C, Miller JI, Prates ET, Walker AM, Amos BK, Mast AE, Justice A, Aronow B, Jacobson D
eLife, 07 2020
The past and future of genetics in pulmonary disease: You can teach an old dog new tricks.
Nogee LM, Hamvas A
Pediatric pulmonology, 07 2020
Childhood rare lung disease in the 21st century: "-omics" technology advances accelerating discovery.
Vece TJ, Wambach JA, Hagood JS
Pediatric pulmonology, 07 2020
CRISPRi-mediated functional analysis of lung disease-associated loci at non-coding regions.
Stuart WD, Guo M, Fink-Baldauf IM, Coleman AM, Clancy JP, Mall MA, Lim FY, Brewington JJ, Maeda Y
NAR genomics and bioinformatics, Jun 2020
Glucocorticoid regulates mesenchymal cell differentiation required for perinatal lung morphogenesis and function.
Bridges JP, Sudha P, Lipps D, Wagner A, Guo M, Du Y, Brown K, Filuta A, Kitzmiller J, Stockman C, Chen X, Weirauch MT, Jobe AH, Whitsett JA, Xu Y
American journal of physiology. Lung cellular and molecular physiology, 08 2020
The elephant in the lung: Integrating lineage-tracing, molecular markers, and single cell sequencing data to identify distinct fibroblast populations during lung development and regeneration.
Riccetti M, Gokey JJ, Aronow B, Perl AT
Matrix biology : journal of the International Society for Matrix Biology, 09 2020
T integrins CD103 and CD49a differentially support adherence and motility after resolution of influenza virus infection.
Reilly EC, Lambert Emo K, Buckley PM, Reilly NS, Smith I, Chaves FA, Yang H, Oakes PW, Topham DJ
Proceedings of the National Academy of Sciences of the United States of America, 06 2020
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