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Single-cell RNA-seq reveals ectopic and aberrant lung-resident cell populations in idiopathic pulmonary fibrosis

Naftali Kaminski^1*, Ivan O. Rosas², Taylor S. Adams¹, Jonas C. Schupp¹, Sergio Poli²

¹Yale School of Medicine, ²Harvard Medical School, ^*Corresponding author

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Description

Single-cell RNA-seq reveals ectopic and aberrant lung-resident cell populations in idiopathic pulmonary fibrosis

LungMAP ID: LMEX0000004393

Organism: human

Stages: adult

Assay type: Single-cell RNA-seq

Technology: 10x Genomics Chromium Single Cell Gene Expression

Reference: Adams et al. (2020)

External databases:

Exploratory Tools
Samples

LungMAP ID	Alt ID	Species	Sex	Race	Age	Health Status
LMSP0000001176	001C	Homo sapiens	Male	White	22 years	No known lung disease
LMSP0000001177	002C	Homo sapiens	Female	White	25 years	No known lung disease
LMSP0000001178	003C	Homo sapiens	Female	White	67 years	No known lung disease
LMSP0000001221	010I	Homo sapiens	Male	White	78 years	IPF
LMSP0000001222	021I	Homo sapiens	Male	White	69 years	IPF
LMSP0000001223	022I	Homo sapiens	Male	White	67 years	IPF
LMSP0000001220	025I	Homo sapiens	Male	White	65 years	IPF
LMSP0000001159	034C	Homo sapiens	Male	Asian	49 years	No known lung disease
LMSP0000001231	034I	Homo sapiens	Male	White	54 years	IPF
LMSP0000001225	040I	Homo sapiens	Male	White	70 years	IPF
LMSP0000001224	041I	Homo sapiens	Male	White	59 years	IPF
LMSP0000001219	051I	Homo sapiens	Male	Other	62 years	IPF
LMSP0000001200	052CO	Homo sapiens	Female	White	62 years	COPD
LMSP0000001228	053I	Homo sapiens	Male	White	60 years	IPF
LMSP0000001201	056CO	Homo sapiens	Female	White	57 years	COPD
LMSP0000001230	063I	Homo sapiens	Male	White	68 years	IPF
LMSP0000001172	065C	Homo sapiens	Female	White	66 years	No known lung disease
LMSP0000001182	081C	Homo sapiens	Male	White	20 years	No known lung disease
LMSP0000001184	084C	Homo sapiens	Male	African American	46 years	No known lung disease
LMSP0000001170	092C	Homo sapiens	Male	Hispanic/Latino	29 years	No known lung disease
LMSP0000001163	098C	Homo sapiens	Female	White	41 years	No known lung disease
LMSP0000001232	123I	Homo sapiens	Male	White	74 years	IPF
LMSP0000001157	133C	Homo sapiens	Female	White	32 years	No known lung disease
LMSP0000001204	135I	Homo sapiens	Male	White	59 years	IPF
LMSP0000001158	1372C	Homo sapiens	Female	White	21 years	No known lung disease
LMSP0000001183	137C	Homo sapiens	Male	White	54 years	No known lung disease
LMSP0000001202	137CO	Homo sapiens	Female	White	73 years	COPD
LMSP0000001205	138I	Homo sapiens	Male	White	56 years	IPF
LMSP0000001206	145I	Homo sapiens	Male	White	67 years	IPF
LMSP0000001185	152CO	Homo sapiens	Male	White	57 years	COPD
LMSP0000001186	153CO	Homo sapiens	Male	White	62 years	COPD
LMSP0000001207	157I	Homo sapiens	Female	White	66 years	IPF
LMSP0000001233	158I	Homo sapiens	Male	White	68 years	IPF
LMSP0000001169	160C	Homo sapiens	Male	White	64 years	No known lung disease
LMSP0000001208	166I	Homo sapiens	Male	White	63 years	IPF
LMSP0000001209	174I	Homo sapiens	Female	White	67 years	IPF
LMSP0000001234	177I	Homo sapiens	Male	White	69 years	IPF
LMSP0000001187	178CO	Homo sapiens	Female	White	58 years	COPD
LMSP0000001210	179I	Homo sapiens	Male	White	70 years	IPF
LMSP0000001188	184CO	Homo sapiens	Female	White	55 years	COPD
LMSP0000001189	186CO	Homo sapiens	Male	White	66 years	COPD
LMSP0000001174	192C	Homo sapiens	Female	White	62 years	No known lung disease
LMSP0000001190	192CO	Homo sapiens	Male	White	66 years	COPD
LMSP0000001191	193CO	Homo sapiens	Male	White	63 years	COPD
LMSP0000001192	194CO	Homo sapiens	Male	White	59 years	COPD
LMSP0000001193	207CO	Homo sapiens	Female	White	60 years	COPD
LMSP0000001167	208C	Homo sapiens	Male	White	23 years	No known lung disease
LMSP0000001211	209I	Homo sapiens	Female	Asian	65 years	IPF
LMSP0000001203	210I	Homo sapiens	Male	White	68 years	IPF
LMSP0000001212	212I	Homo sapiens	Male	White	71 years	IPF
LMSP0000001213	214I	Homo sapiens	Male	White	69 years	IPF
LMSP0000001194	217CO	Homo sapiens	Female	White	70 years	COPD
LMSP0000001160	218C	Homo sapiens	Male	White	29 years	No known lung disease
LMSP0000001214	221I	Homo sapiens	Female	White	67 years	IPF
LMSP0000001168	222C	Homo sapiens	Male	White	65 years	No known lung disease
LMSP0000001215	222I	Homo sapiens	Male	White	59 years	IPF
LMSP0000001216	225I	Homo sapiens	Female	White	70 years	IPF
LMSP0000001161	226C	Homo sapiens	Male	White	32 years	No known lung disease
LMSP0000001217	228I	Homo sapiens	Male	White	56 years	IPF
LMSP0000001196	235CO	Homo sapiens	Female	White	61 years	COPD
LMSP0000001197	237CO	Homo sapiens	Female	White	57 years	COPD
LMSP0000001198	238CO	Homo sapiens	Male	White	66 years	COPD
LMSP0000001195	23CO	Homo sapiens	Male	White	66 years	COPD
LMSP0000001162	244C	Homo sapiens	Male	White	50 years	No known lung disease
LMSP0000001180	253C	Homo sapiens	Female	White	66 years	No known lung disease
LMSP0000001166	296C	Homo sapiens	Female	White	80 years	No known lung disease
LMSP0000001218	29I	Homo sapiens	Male	White	61 years	IPF
LMSP0000001173	388C	Homo sapiens	Male	White	61 years	No known lung disease
LMSP0000001165	396C	Homo sapiens	Female	White	37 years	No known lung disease
LMSP0000001171	439C	Homo sapiens	Female	White	66 years	No known lung disease
LMSP0000001179	454C	Homo sapiens	Female	White	48 years	No known lung disease
LMSP0000001164	465C	Homo sapiens	Male	White	56 years	No known lung disease
LMSP0000001226	47I	Homo sapiens	Male	White	64 years	IPF
LMSP0000001175	483C	Homo sapiens	Male	White	35 years	No known lung disease
LMSP0000001181	484C	Homo sapiens	Male	White	31 years	No known lung disease
LMSP0000001227	49I	Homo sapiens	Male	White	66 years	IPF
LMSP0000001229	59I	Homo sapiens	Female	White	66 years	IPF
LMSP0000001199	8CO	Homo sapiens	Male	White	65 years	COPD