Term: Club cell
LungMAP ID: LMHA0000000143
Synonyms: Clara cell | bronchiolar exocrine cell | nonciliated secretory cell
Definition: The club cell is a non-ciliated, dome-shaped, secretory cell with short microvilli and abundant secretory granules. Its secretory proteins function to protect the bronchiolar epithelium from environmental toxins/irritants. The club cell also has the capacity for self-renewal (maintenance of a progenitor cell pool) and regeneration of the bronchiolar epithelium after injury.